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2016 Annual Report of SCI

Greetings from Dr. Zhizhuang Zhao, Dr. Delong Liu and the editorial office of SCI!

Here we are glad to present the 2016 Annual Report of SCI. In this year of surprise, SCI has made a big step--being indexed in PubMed/PMC! Moreover, SCI has also published many high-quality articles. More information is shown in the Annual Report.

We give our sincere thanks to all our editorial board members, reviewers, authors and readers. We wish you a happy, healthy and prosperous 2017! Read More>>

BCR/ABL can promote CD19+ cell growth but not render them long-term stemness

BCR/ABL stimulates colony formation of CD19+ cells. (A) B-lymphoid colony formation from BCR/ABL vs. vector transduced CD19+ cells and bone marrow (BM) cells, observed under light microscope (×40); (B) quantitation of numbers of colonies formed from BCR/ABL vs. vector transduced CD19+ cells and BM. Mean ± SE are shown. ***, P<0.0001.

Enrichment of skin-derived neural precursor cells from dermal cell populations by altering culture conditions

Immunofluorescence analysis of neurogenic-induced cells showed positive staining for both neuron-specific β-tubulin III and the astrocyte specific marker, glial fibrillary acidic protein (GFAP).

Friend or foe? Mogamulizumab in allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia/lymphoma

Moga depletes not only ATL cells, but also Tregs. Moga depletes ATL cells through ADCC by NK cells, but also depletes Foxp3+ Tregs through ADCC. As a result, moga enhances anti-ATL immunity of anti-ATL NK cells and T cells.

A review of Rett syndrome (RTT) with induced pluripotent stem cells

Human induced pluripotent stem cells (hiPSCs) are pluripotent stem cells generated from somatic cells by the introduction of a combination of pluripotency-associated genes such as OCT4, SOX2, along with either KLF4 and c-MYC or NANOG and LIN28 via retroviral or lentiviral vectors. Most importantly, hiPSCs are similar to human embryonic stem cells (hESCs) functionally as they are pluripotent and can potentially differentiate into any desired cell type when provided with the appropriate cues, but do not have the ethical issues surrounding hESCs.

Mesenchymal stem cell therapy for refractory scleroderma: a report of 2 cases

EsSG of SScl disease activity index at presentation and after treatment by MSC.

Current status of ABL tyrosine kinase inhibitors stop studies for chronic myeloid leukemia

Summary of the ABL tyrosine kinase inhibitor stop studies.

Will targeting PI3K/Akt/mTOR signaling work in hematopoietic malignancies?

The PI3K/Akt/mTOR signaling pathway and the existing molecular targets for therapy, which was indicated by ∆.

Successful treatment of ibrutinib-associated central nervous system hemorrhage with platelet transfusion support

Results of platelet aggregation studies and other coagulation tests which were performed are summarized in this table.

Endothelial progenitor cells in hematologic malignancies

Main features of the two principal endothelial progenitor cells and their abnormalities in myeloproliferative disorders.

Another milestone: Stem Cell Investigation is indexed in PubMed/PMC

On April 25, 2016, an expected and exciting news from the PubMed Central was emailed to the Editorial Office: the Stem Cell Investigation (SCI) has passed all the evaluation required by PubMed Centre (PMC) and is officially accepted for inclusion in PubMed/PMC - an extensive and important biomedical online journal repository! Successful coverage in the prestigious PubMed database not only means the recognition of SCI by international peers, but, more importantly, is one more milestone for SCI to move towards the master publication list of SCI-indexed journals.

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