Article Abstract

MED12 in hematopoietic stem cells—cell specific function despite ubiquitous expression

Authors: Maria-Cristina Keightley, Susan K. Nilsson, Graham J. Lieschke


All cells contain several multi-component molecular machines for executing steps in the fundamental cellular processes of transcription and translation. Paradoxically, despite their ubiquitous expression, individual components of these protein conglomerates are responsible for extraordinarily cell-specific functions.