TY  - JOUR
AU  - Wang, Xinxin
AU  - Zhu, Baohua
AU  - Huang, Zunnan
AU  - Chen, Liyong
AU  - He, Zhiwei
AU  - Zhang, Hua
PY  - 2014
TI  - MicroRNAs as biomarkers in leukemia
JF  - Stem Cell Investigation; Vol 1, No 5 (May 2014): Stem Cell Investigation
Y2  - 2014
KW  - 
N2  - Current diagnostic and prognostic markers still exhibit biological limitation and seeking novel molecular biomarkers is crucial for early clinical diagnosis and in the development of novel strategies for leukemia therapy. Emerging evidence showed that dysregulated microRNAs (miRNAs) play important roles in cancer including leukemia. In this review, we summarized recent progress on the role of miRNAs in leukemia, mainly focusing on recent findings that suggest the potential of miRNAs as biomarkers for diagnosis and prognosis. Notably, the circulating miRNAs were also discussed for the fact that they can be detected in body fluids, and thus represent a novel source of promising biomarkers that may be applied to clinical settings.
UR  - https://sci.amegroups.org/article/view/3833