%0 Journal Article %T A case report of congenital glycogen storage liver cirrhosis treated with bone marrow derived stem cells %A Wehbe, Terek W. %A Chahine, Nassim H. Abi %A Annous, Abdul-Rahman A. %A Ferri, Mohammad A. %A Boulous, Robert C. %A El-Mestrah, Majid F. %J Stem Cell Investigation %D 2017 %B 2017 %9 %! A case report of congenital glycogen storage liver cirrhosis treated with bone marrow derived stem cells %K %X Liver cirrhosis represents a state of end-stage failure that is usually fatal. The condition results in liver dysfunction, recurrent ascites, encephalopathy, renal failure, splenomegaly, bleeding, and a poor quality of life in general. With the current severe shortage of donated organs, the only available treatment in the developing countries remains palliative care. We report a case of congenital metabolic liver cirrhosis due to glycogen storage disease diagnosed at age eight. The patient, a male, received bone marrow derived mononuclear cells (BMMC) at age 16 and again at age 17 with significant improvement of his biochemical liver function tests, ascites build-up, asthenia, splenomegaly and quality of life. Furthermore, liver biopsies showed clear reduction of the inflammation and fibrosis from Ishak score dropped from 3 to 1 paralleling the symptomatic improvement of the patient. %U https://sci.amegroups.org/article/view/16404 %V 4 %N 9 %P %@ 2313-0792