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SCI Annual Report (2020)

Greetings from Dr. Zhizhuang Zhao, Dr. Delong Liu and the Editorial Office of SCI!

We are glad to present the 2020 Annual Report of SCI. There were 24 articles published in SCI and the total retrieval of the journal in PubMed has increased in the past 2020. More information is shown in the Annual Report.

We hereby thank you for your ongoing support in developing the journal as our editorial board members, guest editors, reviewers, authors and readers. We hope that 2021 will bring greater developments to the journal to reach new heights and wish you a happy, healthy and prosperous 2021!

AME entered an official partnership with Publons to enhance wide-ranging recognition for reviewers

AME Publishing Company entered an official partnership with Publons, a product of Clarivate Analytic Company (which owns Web of Science, EndNote, ScholarOne, among many others), as of April 2020. Around 60 AME journals’ peer review systems are now integrated seamlessly into the Publons platform (https://publons.com/about/home). The partnership was done to recognize our expert peer reviewers spontaneously for their review contribution.

Adipose-derived stem cells and their microenvironment (Niche) in type 2 diabetes mellitus

The number of type-2 diabetes mellitus (T2DM) is continuously rising globally. Stromal vascular fraction, which contains adipose tissue stem cells, is an alternative therapy that is developed to overcome T2DM.

Cell pausing method for adipose tissue derived mesenchymal stem cells: comparison of Petaka G3 and ordinary flask

Various methods of cell pausing were applied to prevent proliferation of cultured cells, which either required special medium, using complicated encapsulation method, or using a special flask (Petaka G3 flask).

CD44 expression in stem cells and niche microglia/macrophages following ischemic stroke

CD44 is expressed in stem cells and cells in the niches surrounding them, including inflammatory cells, suggesting that CD44 may play an important role in reparative processes within ischemic areas under neuroinflammatory conditions; in particular, strokes.

Impact of maternal and neonatal factors on umbilical cord CD34⁺ cells

The achievement of optimal number of CD34⁺ umbilical cord stem cells is essential for successful umbilical cord stem cell transplantation. So the aim of this study was to assess the potential effect of both maternal and neonatal factors on the umbilical cord blood CD34⁺ cell count.

Application of the CARE Guideline as reporting standard in the Stem Cell Investigation

The Stem Cell Investigation welcomes case reports which are supposed to report new observations of diseases, clinical findings or novel/unique treatment outcomes relevant to practitioners in the fields of medicine.

For completeness and transparency for published case reports, the Stem Cell Investigation will apply the CARE guidelines (1) as reporting standards for case reports starting from October 14, 2019. For any submission of case report after the date:

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Case Report

COVID-19 induced immune thrombocytopenic purpura: case report

Sara Ashraf, Mohamed Alsharedi

Stem Cell Investigation

2021;

(09 July 2021)

PDF Full Text Reporting Checklist COI Form Open Access

Review Article

Accentuating the sources of mesenchymal stem cells as cellular therapy for osteoarthritis knees—a panoramic review

Sathish Muthu, Madhan Jeyaraman, Rashmi Jain, Arun Gulati, Naveen Jeyaraman, Gollahalli Shivashankar Prajwal, Prabhu Chandra Mishra

Stem Cell Investigation

2021;

(09 July 2021)

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Original Article

Effect of mesenchymal stem cells versus aloe vera on healing of deep second-degree burn

Nahla Imbarak, H. Ismail Abdel-Aziz, Lamiaa M. Farghaly, Somaya Hosny

Stem Cell Investigation

2021;

(15 June 2021)

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Review Article

Platelet lysate for COVID-19 pneumonia—a newer adjunctive therapeutic avenue

Madhan Jeyaraman, Sathish Muthu, Manish Khanna, Rashmi Jain, Talagavadi Channaiah Anudeep, Purushothaman Muthukanagaraj, Sushmitha Eachagattada Siddesh, Arun Gulati, Ajay Shringeri Satish, Naveen Jeyaraman, Venus Khanna

Stem Cell Investigation

2021;

(08 June 2021)

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Review Article

Safety and therapeutic potential of human bone marrow-derived mesenchymal stromal cells in regenerative medicine

Ashwini P. Aithal, Laxminarayana K. Bairy, Raviraja N. Seetharam

Stem Cell Investigation

2021;

(11 May 2021)

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Original Article

Vitamin E and selenium improve mesenchymal stem cell conditioned media immunomodulatory effects

Fereshteh Ghasemi, Majid Khoshmirsafa, Elahe Safari, Marzieh Asgari, Mehdi Alemrajabi, Shahrzad Nojehdehi, Samane Khorrami

Stem Cell Investigation

2021;

(07 May 2021)

PDF Full Text Reporting Checklist COI Form Open Access

Original Article

Development of Donor Recipient Chimeric Cells of bone marrow origin as a novel approach for tolerance induction in transplantation

Joanna Cwykiel, Maria Madajka-Niemeyer, Maria Siemionow

Stem Cell Investigation

2021;

(19 April 2021)

PDF Full Text Reporting Checklist COI Form Open Access

Review Article

Exosomal therapy—a new frontier in regenerative medicine

Sathish Muthu, Asawari Bapat, Rashmi Jain, Naveen Jeyaraman, Madhan Jeyaraman

Stem Cell Investigation

2021;

(02 April 2021)

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Original Article

Expression of mRNA TNFα and level of protein TNFα after exposure sCD40L in bone marrow mononuclear cells of myelodysplastic syndromes

Anggraini Iriani, Rahayuningsih D. Setiabudy, Siti B. Kresno, Aru W. Sudoyo, Saptawati Bardosono, Andhika Rachman, Alida R. Harahap, Mansyur Arief

Stem Cell Investigation

2021;

(29 March 2021)

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Brief Report

A novel therapeutic combination of mesenchymal stem cells and stigmasterol to attenuate osteoarthritis in rodent model system— a proof of concept study

Samuel Joshua Pragasam Sampath, Nagasuryaprasad Kotikalapudi, Vijayalakshmi Venkatesan

Stem Cell Investigation

2021;

(23 March 2021)

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Review Article

Human-animal interspecies chimerism via blastocyst complementation: advances, challenges and perspectives: a narrative review

Yuhang Li, Ke Huang

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Case Report

Autologous bone marrow aspirate concentrate (BMAC) for treatment of keratocystic odontogenic tumour (KCOT) —a case report

Manimaran Kanakaraj, Sangeetha Manoharan, Sivashankaran Srinivas, Marudhamani Chinnannan, Avinash Gandhi Devadas, Rashmi Jain, Sathish Muthu, Madhan Jeyaraman

PDF Reporting Checklist COI Form

Response of advanced cutaneous squamous cell carcinoma to immunotherapy: case report

Sara Ashraf, Mohamed Alsharedi

PDF Reporting Checklist COI Form

Original Article

Comparison of stem cells from human exfoliated deciduous posterior teeth with varying levels of root resorption

Meghna Bhandary, Shama Rao, Alandur Veena Shetty, Basavarajappa Mohana Kumar, Amitha Mahesh Hegde, Rachaita Chhabra

PDF Reporting Checklist COI Form

Patterns of leukocyte recovery predict infectious complications after CD19 CAR-T cell therapy in a real-world setting

Astha Thakkar, Zhu Cui, Stephen Zachary Peeke, Nishi Shah, Kith Pradhan, Amanda Lombardo, Fariha Khatun, Jennat Mustafa, Alyssa De Castro, Kailyn Gillick, Felisha Joseph, Anjali Naik, Shafia Rahman, Angelica D'Aiello, Richard Elkind, Susan Sakalian, Karen Fehn, Karen Wright, Michelly Abreu, Latoya Townsend Nugent, Nicole Chambers, Rosmi Mathew, Donika Binakaj, Randin Nelson, Carlo Palesi, Monika Paroder, Joan Uehlinger, Yanhua Wang, Yang Shi, Xingxing Zang, Hao Wang, Christopher Nishimura, Xiaoxin Ren, Ulrich G. Steidl, Kira Gritsman, Murali Janakiram, Noah Kornblum, Olga Derman, Ioannis Mantzaris, Aditi Shastri, Rachel Bartash, Yoram Puius, Margaret McCort, Mendel Goldfinger, Lizamarie Bachier-Rodriguez, Amit Verma, Ira Braunschweig, R. Alejandro Sica

PDF Reporting Checklist COI Form

Review Article

Cancer stem cells: progress and challenges in lung cancer

Amanda K. Templeton, Shinya Miyamoto, Anish Babu, Anupama Munshi, Rajagopal Ramesh

Recent advances and novel agents for FLT3 mutated AML

Rahul Pawar, Omar Preet Singh Bali, Bharat Kumar Malhotra, Gurpreet Lamba

Regulatory factors of induced pluripotency: current status

Wei Zhao, Bo Ning, Chen Qian

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

MicroRNAs as biomarkers in leukemia

Xinxin Wang, Baohua Zhu, Zunnan Huang, Liyong Chen, Zhiwei He, Hua Zhang

Regulation of cancer stem cells by RING finger ubiquitin ligases

Bin Kang, Xiao-Hong Sun

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

Commentary

Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights

Yamei Chen, Delong Liu

Case Report

Cutaneous metastasis as an initial presentation of lung adenocarcinoma with KRAS mutation: a case report and literature review

Huijuan Liao, Shenhong Wu, Stephen R. Karbowitz, Nora Morgenstern, David R. Rose

Review Article

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

MicroRNAs as biomarkers in leukemia

Xinxin Wang, Baohua Zhu, Zunnan Huang, Liyong Chen, Zhiwei He, Hua Zhang

The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute

Jilong Yang, Zhiwu Ren, Xiaoling Du, Mengze Hao, Wenya Zhou

Targeting cancer stem cells with oncolytic virus

Yin Tong, Wenbin Qian

Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation

Tianyu Guo, Xuejun Wang, Yigong Qu, Yu Yin, Tao Jing, Qing Zhang

Cancer stem cells and exosome signaling

Bethany N. Hannafon, Wei-Qun Ding

Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition

Yu Liu, Deguang Kong, Hua Wu, Xun Yuan, Hanxiao Xu, Cuntai Zhang, Gaosong Wu, Kongming Wu

Expression and function of P2 receptors in hematopoietic stem and progenitor cells

Wenli Feng, Lina Wang, Guoguang Zheng

Current insights into the diagnosis and treatment of inherited bone marrow failure syndromes in China

Xiaofan Zhu

Research Highlights

Shp2 regulates leukemic stem cell frequency in MLL-rearranged acute myeloid leukemia

Jie Wu

Editorial

Stem nourished by branches: glioblastomas co-opt classic neurotrophic factor signaling to maintain stem-like cell pool

Rukayat Taiwo, Tatenda Mahlokozera, Albert H. Kim

Evolutionarily diverse mechanisms of germline specification among mammals: what about us?

Shino Mitsunaga, Toshi Shioda

Epigenomic and single-cell profiling of human spermatogonial stem cells

Akihiko Sakashita, Yu-Han V. Yeh, Satoshi H. Namekawa, Shau-Ping Lin

The puzzling mechanism of compensatory lung growth

Steven J. Mentzer

Vaccination with induced pluripotent stem cells confers protection against cancer

Kavitha Yaddanapudi, Chi Li, John W. Eaton

Commentary

Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights

Yamei Chen, Delong Liu

Case Report

Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening

Keyur Thakar, Kaushal Parikh, Yamei Chen, Delong Liu

Original Article

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells

Gay Carter, Rekha Patel, André Apostolatos, Michel Murr, Denise R. Cooper, Niketa A. Patel

Reverse transcriptase and intron number evolution

Kemin Zhou, Alan Kuo, Igor V. Grigoriev

Interleukin 8/KC enhances G-CSF induced hematopoietic stem/ progenitor cell mobilization in Fancg deficient mice

Yan Li, Wen Xing, Yong-Zheng He, Shi Chen, Steven D. Rhodes, Jin Yuan, Yuan Zhou, Jun Shi, Jie Bai, Feng-Kui Zhang, Wei-Ping Yuan, Tao Cheng, Ming-Jiang Xu, Feng-Chun Yang

Quantitative analyses of myelofibrosis by determining hydroxyproline

Wanke Zhao, Wan-Ting Tina Ho, Zhizhuang Joe Zhao

Journal Highlight more

Stem Cell Investigation is an international, open access, peer-reviewed, PubMed-indexed online journal covering basic, translational, and clinical research on all aspects of stem cells, e.g. embryonic stem cells, induced pluripotent stem cells, adult tissue-specific stem/progenitor cells, cancer stem like cells, stem cell niche, stem cell technology, stem cell based drug discovery, and regenerative medicine.

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