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Stem Cell Investigation (SCI) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Stem Cell Investigation (SCI) is among the list of COPE membership.

AME entered an official partnership with Publons to enhance wide-ranging recognition for reviewers

AME Publishing Company entered an official partnership with Publons, a product of Clarivate Analytic Company (which owns Web of Science, EndNote, ScholarOne, among many others), as of April 2020. Around 60 AME journals’ peer review systems are now integrated seamlessly into the Publons platform (https://publons.com/about/home). The partnership was done to recognize our expert peer reviewers spontaneously for their review contribution.

Adipose-derived stem cells and their microenvironment (Niche) in type 2 diabetes mellitus

The number of type-2 diabetes mellitus (T2DM) is continuously rising globally. Stromal vascular fraction, which contains adipose tissue stem cells, is an alternative therapy that is developed to overcome T2DM.

Cell pausing method for adipose tissue derived mesenchymal stem cells: comparison of Petaka G3 and ordinary flask

Various methods of cell pausing were applied to prevent proliferation of cultured cells, which either required special medium, using complicated encapsulation method, or using a special flask (Petaka G3 flask).

CD44 expression in stem cells and niche microglia/macrophages following ischemic stroke

CD44 is expressed in stem cells and cells in the niches surrounding them, including inflammatory cells, suggesting that CD44 may play an important role in reparative processes within ischemic areas under neuroinflammatory conditions; in particular, strokes.

Impact of maternal and neonatal factors on umbilical cord CD34⁺ cells

The achievement of optimal number of CD34⁺ umbilical cord stem cells is essential for successful umbilical cord stem cell transplantation. So the aim of this study was to assess the potential effect of both maternal and neonatal factors on the umbilical cord blood CD34⁺ cell count.

Application of the CARE Guideline as reporting standard in the Stem Cell Investigation

The Stem Cell Investigation welcomes case reports which are supposed to report new observations of diseases, clinical findings or novel/unique treatment outcomes relevant to practitioners in the fields of medicine.

For completeness and transparency for published case reports, the Stem Cell Investigation will apply the CARE guidelines (1) as reporting standards for case reports starting from October 14, 2019. For any submission of case report after the date:

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Letters to the editor

Immunophenotypic analysis of human adipose-derived stem cells through multi-color flow cytometry

Paolo Giuseppe Limoli, Marcella Nebbioso

Stem Cell Investigation

2023;

10:

(09 June 2023)

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Original Article

Femur bone marrow from brain death deceased donors as source of human mesenchymal stromal cells for cell therapy

Lourdes Echarte, Alexandra Sujanov, Daniel Machin, Natalia Marquisá, Cristina Touriño

Stem Cell Investigation

2023;

10:

(23 May 2023)

PDF Full Text (158) Reporting Checklist COI Form Open Access

Case Report

Malignant clonal evolution from high proportion of monocytes in patients with aplastic anemia: a case report

Qiuhao Fu, Lingling Liu, Yingmei Li

Stem Cell Investigation

2023;

10:

(15 May 2023)

PDF Full Text (238) Reporting Checklist COI Form Open Access

Original Article

Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells

Wataru Isono, Tomoyuki Kawasaki, Justin K. Ichida, Kazunori Nagasaka, Osamu Hiraike, Akihiro Umezawa, Hidenori Akutsu

Stem Cell Investigation

2023;

10:

(19 April 2023)

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Review Article

Macrophages and stem/progenitor cells interplay in adipose tissue and skeletal muscle: a review

Malgorzata Kloc, Ahmed Uosef, Henry V. Ubelaker, Jacek Z. Kubiak, Rafik M. Ghobrial

Stem Cell Investigation

2023;

10:

(13 April 2023)

PDF Full Text (361) COI Form Open Access

Letters to the editor

Immune reconstitution profile after allogeneic hematopoietic stem cell transplantation with post-transplant cyclophosphamide

Manuel Espinoza-Gutarra, Ayman Saad, Omer Jamy

Stem Cell Investigation

2023;

10:

(10 April 2023)

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Original Article

Neurogenic marker expression in differentiating human adipose derived adult mesenchymal stem cells

Neus Gomila Pelegri, Bruce K. Milthorpe, Catherine A. Gorrie, Jerran Santos

Stem Cell Investigation

2023;

10:

(23 March 2023)

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Review Article

Current status and prospects of regenerative medicine for spinal cord injury using human induced pluripotent stem cells: a review

Mitsuhiro Inoue, Ryo Yamaguchi, Ching Chi Jimmy He, Atsushi Ikeda, Hideyuki Okano, Jun Kohyama

Stem Cell Investigation

2023;

10:

(10 March 2023)

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Editorial Commentary

Recreating heterogeneity of bladder cancer microenvironment to study its recurrences and progression

François Bordeleau, David Brownell, Stephane Chabaud, Marc-Etienne Huot, Stephane Bolduc

Stem Cell Investigation

2023;

10:

(07 March 2023)

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Review Article

The role of macrophages in fracture healing: a narrative review of the recent updates and therapeutic perspectives

Bianca Braga Frade, Rhayra Braga Dias, Sara Gemini Piperni, Danielle Cabral Bonfim

Stem Cell Investigation

2023;

10:

(08 February 2023)

PDF Full Text (735) Reporting Checklist COI Form COI Form Open Access

Methodology

Optimization of adeno-associated virus (AAV) gene delivery into human bone marrow stem cells (hBMSCs)

Shaomian Yao, Weiqiong Rong, Yuanying Yuan

Stem Cell Investigation

2023;

10:

(02 February 2023)

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Original Article

Exosome-based cancer vaccine for prevention of lung cancer

Shuhan Meng, Aaron G. Whitt, Bryce F. Stamp, John W. Eaton, Chi Li, Kavitha Yaddanapudi

Stem Cell Investigation

2023;

10:

(09 January 2023)

PDF Full Text (886) Reporting Checklist COI Form Open Access

Editorial Commentary

A selective type of autophagy to maintain glioma stem cell activity

Khushbu Patel, Esperanza Arias

Stem Cell Investigation

2023;

10:

(06 January 2023)

PDF Full Text (753) COI Form Open Access

Original Article

Creation of human hematopoietic chimeric cell (HHCC) line as a novel strategy for tolerance induction in transplantation

Maria Siemionow, Sonia Brodowska, Klaudia Różczka, Claire Roesler

Stem Cell Investigation

2022;

(19 December 2022)

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Review Article

Leukemic stem cells and advances in hematopoietic stem cell transplantation for acute myeloid leukemia: a narrative review of clinical trials

Vikram Sumbly, Ian Landry, Christina Sneed, Qamar Iqbal, Anu Verma, Tenzin Dhokhar, Adeel Masood, Akshay Amaraneni

Stem Cell Investigation

2022;

(05 December 2022)

PDF Full Text (1039) Reporting Checklist COI Form Open Access

Editorial Commentary

Is there a role for allogeneic hematopoietic stem cell transplantation for refractory follicular lymphoma?

Yang Yang, Xia Bi, Mia Gergis, Usama Gergis

Stem Cell Investigation

2022;

(14 November 2022)

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Case Report

An autologous humanized patient-derived xenograft (PDX) model for evaluation of nivolumab immunotherapy in renal cell cancer: a case report

Yubin Kang, Andrew J. Armstrong, David S. Hsu

Stem Cell Investigation

2022;

(08 November 2022)

PDF Full Text (1386) Reporting Checklist COI Form Open Access

Review Article

Adverse events, side effects and complications in mesenchymal stromal cell-based therapies

Denis S. Baranovskii, Ilya D. Klabukov, Nadezhda V. Arguchinskaya, Anna O. Yakimova, Anastas A. Kisel, Elena M. Yatsenko, Sergei A. Ivanov, Peter V. Shegay, Andrey D. Kaprin

Stem Cell Investigation

2022;

(08 November 2022)

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Editorial Commentary

BRD4 regulates the induction and maintenance of cancer stem cells in squamous cell carcinoma

Mawieh Hamad, Amjad Ali, Jibran Sualeh Muhammad

Stem Cell Investigation

2022;

(28 October 2022)

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Editorial Commentary

Eph receptor B2 (EPHB2) regulates cancer stem cell-like properties in hepatocellular carcinoma

Jhin Jieh Lim, Edward Kai-Hua Chow, Tan Boon Toh

Stem Cell Investigation

2022;

(19 October 2022)

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Review Article

Cancer stem cells: progress and challenges in lung cancer

Amanda K. Templeton, Shinya Miyamoto, Anish Babu, Anupama Munshi, Rajagopal Ramesh

Review Article

Recent advances and novel agents for FLT3 mutated AML

Rahul Pawar, Omar Preet Singh Bali, Bharat Kumar Malhotra, Gurpreet Lamba

Review Article

Regulatory factors of induced pluripotency: current status

Wei Zhao, Bo Ning, Chen Qian

Review Article

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Review Article

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

Review Article

MicroRNAs as biomarkers in leukemia

Xinxin Wang, Baohua Zhu, Zunnan Huang, Liyong Chen, Zhiwei He, Hua Zhang

Review Article

Regulation of cancer stem cells by RING finger ubiquitin ligases

Bin Kang, Xiao-Hong Sun

Review Article

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

Commentary

Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights

Yamei Chen, Delong Liu

Case Report

Cutaneous metastasis as an initial presentation of lung adenocarcinoma with KRAS mutation: a case report and literature review

Huijuan Liao, Shenhong Wu, Stephen R. Karbowitz, Nora Morgenstern, David R. Rose

Review Article

TNF-α, a good or bad factor in hematological diseases?

Tian Tian, Min Wang, Daoxin Ma

Review Article

Reactive oxygen species in eradicating acute myeloid leukemic stem cells

Hui Zhang, Hai Fang, Kankan Wang

Review Article

Cancer stem cells as a potential therapeutic target in breast cancer

Mingzhi Zhang, Zhaoming Li, Xudong Zhang, Yu Chang

Review Article

MicroRNAs as biomarkers in leukemia

Xinxin Wang, Baohua Zhu, Zunnan Huang, Liyong Chen, Zhiwei He, Hua Zhang

Review Article

The role of mesenchymal stem/progenitor cells in sarcoma: update and dispute

Jilong Yang, Zhiwu Ren, Xiaoling Du, Mengze Hao, Wenya Zhou

Review Article

Targeting cancer stem cells with oncolytic virus

Yin Tong, Wenbin Qian

Review Article

Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation

Tianyu Guo, Xuejun Wang, Yigong Qu, Yu Yin, Tao Jing, Qing Zhang

Review Article

Cancer stem cells and exosome signaling

Bethany N. Hannafon, Wei-Qun Ding

Review Article

Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition

Yu Liu, Deguang Kong, Hua Wu, Xun Yuan, Hanxiao Xu, Cuntai Zhang, Gaosong Wu, Kongming Wu

Review Article

Expression and function of P2 receptors in hematopoietic stem and progenitor cells

Wenli Feng, Lina Wang, Guoguang Zheng

Review Article

Current insights into the diagnosis and treatment of inherited bone marrow failure syndromes in China

Xiaofan Zhu

Research Highlights

Shp2 regulates leukemic stem cell frequency in MLL-rearranged acute myeloid leukemia

Jie Wu

Editorial

Stem nourished by branches: glioblastomas co-opt classic neurotrophic factor signaling to maintain stem-like cell pool

Rukayat Taiwo, Tatenda Mahlokozera, Albert H. Kim

Editorial

Evolutionarily diverse mechanisms of germline specification among mammals: what about us?

Shino Mitsunaga, Toshi Shioda

Editorial

Epigenomic and single-cell profiling of human spermatogonial stem cells

Akihiko Sakashita, Yu-Han V. Yeh, Satoshi H. Namekawa, Shau-Ping Lin

Editorial

The puzzling mechanism of compensatory lung growth

Steven J. Mentzer

Editorial

Vaccination with induced pluripotent stem cells confers protection against cancer

Kavitha Yaddanapudi, Chi Li, John W. Eaton

Commentary

Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights

Yamei Chen, Delong Liu

Case Report

Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening

Keyur Thakar, Kaushal Parikh, Yamei Chen, Delong Liu

Original Article

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells

Gay Carter, Rekha Patel, André Apostolatos, Michel Murr, Denise R. Cooper, Niketa A. Patel

Original Article

Reverse transcriptase and intron number evolution

Kemin Zhou, Alan Kuo, Igor V. Grigoriev

Original Article

Interleukin 8/KC enhances G-CSF induced hematopoietic stem/ progenitor cell mobilization in Fancg deficient mice

Yan Li, Wen Xing, Yong-Zheng He, Shi Chen, Steven D. Rhodes, Jin Yuan, Yuan Zhou, Jun Shi, Jie Bai, Feng-Kui Zhang, Wei-Ping Yuan, Tao Cheng, Ming-Jiang Xu, Feng-Chun Yang

Original Article

Quantitative analyses of myelofibrosis by determining hydroxyproline

Wanke Zhao, Wan-Ting Tina Ho, Zhizhuang Joe Zhao

Journal Highlight more

Stem Cell Investigation is an international, open access, peer-reviewed, PubMed-indexed online journal covering basic, translational, and clinical research on all aspects of stem cells, e.g. embryonic stem cells, induced pluripotent stem cells, adult tissue-specific stem/progenitor cells, cancer stem like cells, stem cell niche, stem cell technology, stem cell based drug discovery, and regenerative medicine.