TY - JOUR AU - Li, Yangqiu AU - Xu, Ling PY - 2015 TI - Evaluation of TCR repertoire diversity in patients after hematopoietic stem cell transplantation JF - Stem Cell Investigation; Vol 2, No 9 (September 2015): Stem Cell Investigation Y2 - 2015 KW - N2 - T-cell receptor (TCR) repertoire analyses have been widely used to identify T cell populations of interest in cancer and autoimmunity and for characterizing immune repertoire reconstitution after hematopoietic stem cell transplantation (HSCT). Several decades of development and progress have led to the use of techniques for evaluating TCR repertoires in a more comprehensive, unbiased and fast manner, and the mechanisms of T cell immune reconstitution after HSCT and the new approaches used for recovering T cell repertoire diversity post HSCT have been more exhaustively documented to some degree. To better understand and characterize this progress, here we review recent studies on TCR repertoire diversity recovery in patients with leukemia and autoimmune disease who have received HSCT, impact factors and improvements in approaches for TCR repertoire recovery after HSCT. UR - https://sci.amegroups.org/article/view/7883