TY - JOUR AU - Taiwo, Rukayat AU - Mahlokozera, Tatenda AU - Kim, Albert H. PY - 2018 TI - Stem nourished by branches: glioblastomas co-opt classic neurotrophic factor signaling to maintain stem-like cell pool JF - Stem Cell Investigation; Vol 5, No 6 (July 2018): Stem Cell Investigation Y2 - 2018 KW - N2 - Glioblastoma is the most aggressive and highest grade (World Health Organization grade 4) of diffuse gliomas and is also the most common primary central nervous system malignancy in adults, accounting for 45% of brain cancers (1). Despite multimodality treatment consisting of maximal, safe, surgical resection followed by temozolomide (TMZ) chemotherapy and radiotherapy, the prognosis of glioblastoma remains challenging with a 5-year survival rate of only 9.8% (2). UR - https://sci.amegroups.org/article/view/20486