Article Abstract

E-cadherin adhesion-mediated Wnt activation for mesoderm specification in human embryonic stem cells needs a soft mattress

Authors: Andrew Sulaiman, Li Li, Lisheng Wang


While the roles of transcription factors and morphogens in stem cell differentiation have been well studied, little is known about how extracellular forces are translated into intracellular signals to direct tissue specific differentiation and development.